The aim of the course is to give the students a fundamental understanding of the interplay between the many different intracellular reactions, and especially how the fluxes through the different pathways are regulated; with special focus on pathways leading to industrially relevant products like primary metabolites, antibiotics, industrial enzymes, and pharmaceutical proteins. A central aspect of the course is to identify the optimal strategy for introducing directed genetic changes in the microorganisms with the aim of obtaining better production strains. Analysis of the interaction between different cellular reactions is a central element in the course, and tools from functional genomics and systems biology will therefore be describes. This will involve tools like DNA arrays, proteomics and bioinformatics.
Eduard Kerkhoven firstname.lastname@example.org Office: Department of Biology and Biological Engineering, Systems and Synthetic Biology