Om kursen
DNA, regarding structure, dynamics and interactions in solution. It is a literature course where each participant gives a presentation (2h) of a chapter of the book. Examination is through 1) the oral presentation, 2) weekly assignments dealing with each lecture, and 3) a few broader assignments at the end of the course.
Nitrogen bases, nucleosides, nucleotides. Chemical and enzymatic methods, Sequencing. DNA structure. UV-vis and IR spectroscopy. Theoretical methods. Size and shape of DNA coils. Conformational change. Circular DNA. Interactions with water, ions, dyes, drugs and proteins. Coil-compaction in vitro and packaging in bacteriophages.
Application information
Application is made by sending an email to Fredrik Westerlund or Marcus Wilhelmsson
Nitrogen bases, nucleosides, nucleotides. Chemical and enzymatic methods, Sequencing. DNA structure. UV-vis and IR spectroscopy. Theoretical methods. Size and shape of DNA coils. Conformational change. Circular DNA. Interactions with water, ions, dyes, drugs and proteins. Coil-compaction in vitro and packaging in bacteriophages.
Application information
Application is made by sending an email to Fredrik Westerlund or Marcus Wilhelmsson
Mer information
Fredrik Westerlund, email: bfredrik.westerlund@chalmers.se
Department of Biology and Biological Engineering
Marcus Wilhelmsson, email: marcus.wilhelmsson@chalmers.se
Chemistry and Chemical Engineering
Kurslitteratur
Nucleic Acids. Structures, Properties and Functions.
Bloomfield, V.A., Crothers, D.M., and Tinoco, I.
University Science Books, Sausalito 2000
Bloomfield, V.A., Crothers, D.M., and Tinoco, I.
University Science Books, Sausalito 2000
Föreläsare
Fredrik Westerlund and Marcus Wilhelmsson
