Carbohydrate-active enzymes are the biological catalysts that synthesize and break down the multitude of complex carbohydrate structures found in nature. Our research efforts primarily focus on enzymes that deconstruct key components in plant biomass, such as cellulose and hemicelluloses, and spans from fundamental to applied settings.
Ongoing projects revolve around enzyme discovery coupled to structure-function studies using detailed biochemical analyses and X-ray crystallography, where a broad understanding of the microbial degradation of biomass is sought. Applied projects involve immobilization of enzymes for production of high-value chemicals, and development of novel enzyme cocktails for biomass hydrolysis.
Ongoing centers and projects:
- Wallenberg wood science center
- Critical redox processes for efficient saccharification of lignocellulose
- Development of thermostable enzyme cocktails
- Enzyme discovery and production in Vietnam for the production of sustainable biofuels and biochemicals
- Immobilization of enzymes in mesoporous materials (part of the Linneaus Centre SUPRA)
- Mapping of unstudied cellulose-degrading mechanisms in soil bacteria
- Optimized esterase biocatalysts for cost-effective industrial production (OPTIBIOCAT)
- Structure-function studies of enzymes cleaving covalent bonds between lignin and hemicelluloses