Post-graduate course

 

The course is suitible to PhD students or researchers with a background in bio-technology, chemical engineering or biochemistry. Accredited with 5 ECTSpoints.

The course fee is 3.500 SEK (~330 €) for academic participants and 8.000 SEK (~840 €) for participants from the industry.
The course fee includes all course material, social events, amenities, 6 lunches and 3 dinners. Accommodation will be arranged for those requiring it (2.000 SEK, 26^th of October – 1st of November, in 4 or 5-bedrooms, at Göteborgs Vandrarhem (Gothenburg Hostel).

 

The registration form is available here. Registration by the 18^th of September 2019.

 

Sunday October 27^th
Introduction, raw material composition and sources
09:00-09:30 Course introduction. Round the table presentations (LO)
09:30-10:15 Lignocellulose conversion to chemicals – from stand-alone facilities to biorefineries
(LO)
10:15-10:30 Coffee
10:30-11:15 Plant cell wall fundamentals (JL)
11:15-12:00 Basic raw material analytics: HPLC, HPAEC, reducing sugars (LO)
12:00-13:00 Lunch – 10:an
13:00-14:00 Fractionation and pre-treatment methods (MG)
14:00-15:00 Mass spectrometric-based glycomic analysis of lignocellulosic materials (FVD)
15:00-15:30 Coffee
15:30-16:15 Inhibitors in lignocellulose hydrolysates (LO)
16:15-17:00 Enzyme discovery for biorefinery applications (JL)
17:00-17:45 Exercises and discussion (FVD, LO, MG)
18:00 Dinner at Chalmers, student poster presentation, get-together

Monday October 28^th
Characterization & enzymatic degradation of lignocelluloses
09:00-09:45 Challenges in sample preparation and analysis of lignocellulose polymeric materials
(MH)
09:45-10:00 Coffee
10:00-11:00 Abiotic reactions in pretreated lignocellulose (KSJ)
11:00-11:45 Exercises and discussion (KSJ)
12:00-13:00 Lunch - kårhuset
13:00-13:45 Enzymatic hydrolysis of lignocellulose - introduction (LO/JL)
13:45-14:45 Cellulolytic enzymes (LO)
14:45-15:15 Coffee
15:15-16:00 Mannolytic and xylanolytic enzymes (EM)
16:00-16.45 Bacterial anaerobic degradation of biomass (JL)
16:45-17:30 Exercises and discussion (JL, LO)

Tuesday October 29^th
Enzymes and their action & Hot topics seminar
09:00-10:00 Lytic Polysaccharide Monooxygenases (LPMOs) and other redox enzymes in polysaccharide degradation – fundamental and applied aspects (VE)
10:00-10:15 Coffee
10:15-11.15 Kinetics and design of cellulases (PW)
11:15-12:00 Exercise: Enzyme classification & CAZY (JL)
12:00-13:00 Lunch – 10:an
13:00-13:20 Lisbeth Olsson: Perspectives, challenges and trends towards biorefineries and a new bioeconomy
13:20-14:00 Phillip Pope: Wood2Feed: Can we use woody biomass as feed ingredients and improve diets in livestock?
14:00-14:40 Richard van Kranenburg: Bacterial cell factories for the biobased economy
14:40-15:10 Coffee
15:10-15:50 Emma Master – Enzymes for polysaccharide functionalization
15:50-16:30 Björn Alriksson – From wood to food
16:30-17.10 Kaspar Valgepea - Capturing waste carbon using acetogen gas fermentation
18:30 Course Dinner downtown Gothenburg M/S Marieholm

Wednesday October 30^th
Microorganisms
09:00-10:00 Lignin acting enzymes (KH)
10:00-10:15 Coffee
10:15-11:15 Cell propagation (LO)
11:15-12:00 Exercises and discussion (KH, CG)
12:00-13:00 Lunch
13:00-13:45 Different products of microbial metabolism and thermodynamic driving forces (YN)
13:45-14:30 Strain improvement by mutagenesis, directed evolution and screening (CG)
14:30-15:00 Coffee
15:00-15:45 Strain improvement by metabolic engineering (YN)
15:45-16.30 Development of industrial yeast strains (YN)
16:30-17.30 Exercises and discussion (YN,CG)

Thursday October 31^st
Fermentation processes
09:00-09:45 Industrial production hosts and bioproducts (YN)
09:45-10:30 Lignocellulose hydrolysate fermentation: microbial robustness (LO)
10:30-10:45 Coffee
10:45-11:45 Exercises and discussion (CJF, LO)
12:00-13:00 Lunch, kårhuset
13:00-13:45 Fermentation basics: important fermentation variables and mode of operation of bioreactors (CJF)
13:45-14:30 Fermentation basics: important fermentation variables and mode of operation of bioreactors - continued (CJF)
14:30-15:00 Coffee
15:00-15:45 Fermentation of lignocellulosic media: mode of operation and strategies (CJF)
15:45-16.45 Microbial detoxification of lignocellulose hydrolysates and upgrading of lignin (SS)
16:45-17.30 Exercises and discussion (CJF, LO)
17:30-18.00 Concluding discussions, questions and sum-up
18:00 Pizza at the department and lab visit

Friday November 1^st
Sustainability, down-stream processing etc.
Exam
09:00-09:45 Enzyme production by filamentous fungi: from secretion to large scale production (LO)
09:45-10:45 Bioenergy and biomaterials sustainability issues (CC)
10:45-11:00 Coffee
11:00-12:00 Down-stream processing (IS)
12:00-13:00 Lunch – 10:an
13:00-15:00 Written exam
Good-bye and wrap up over coffee

 

Lisbeth Olsson (Course Responsible) lisbeth.olsson@chalmers.se  

Yvonne Nygård yvonne.nygard@chalmers.se