Precision Nutrition Forum

Precision Nutrition Forum, 1st edition – Gothenburg:

​Using Multi-OMICs for Data-Driven Systems Epidemiology - Towards Precision Nutrition


Scope

Metabolic diseases, including obesity, type 2 diabetes, cardiovascular disease, and some cancers, pose a major burden on public health systems, accounting for most global chronic diseases and deaths. These conditions share complex underlying pathophysiology interacting with environmental, lifestyle, and dietary factors. It is widely recognized that poor diet quality contributes substantially to these conditions, but the mechanisms by which diet influences metabolic health are not well studied. Emerging tools and technologies, including metabolomics profiling, can help elucidate mechanisms underpinning the relationship between diet and metabolic disease. In addition, integrating metabolomics with other omics data is critical to understanding interindividual differences in the metabolic response to dietary interventions. Therefore, OMICs profiling in nutritional studies can elucidate the biological role of diet composition in chronic disease etiology and expand the evidence base of dietary guidelines in the general population. Moreover, a thorough understanding of the molecular links between diet and disease risk could pave the way for precision nutrition, where dietary advice and interventions are tailored to individuals based on their health status, lifestyle factors, social-cultural factors, and genetics and other molecular phenotypes.
 
The goal of the Precision Nutrition Forum, 1st edition – Gothenburg​ is to bring together interdisciplinary expertise in nutritional epidemiology, high-throughput omics technologies (genomics, metabolomics, metagenomics, and proteomics), and data science and present the latest concepts and advances in precision nutrition research. The Forum will gather world-leading multi-omics and precision nutrition experts from Europe and the US, with the goal of fostering international collaboration through the Swedish cohort infrastructures and the national Data-Driven Life Science initiative (DDLS). 

Hosted at Chalmers University of Technology, Gothenburg, Sweden

Chalmers scientific organization: Clemens Wittenbecher & Rikard Landberg
External scientific organization committee members: Marta Guasch-Ferré, Jordi Merino
Head of administrative organization: Mia Gartner

Funded by: Hjärtlungfonden, Chalmers Area of Advance Health Engineering, Cancerfonden and DDLS

Registration


Link to registration, deadline: 2nd September 2022
  
Link to abstract submission, deadline: 12th August 2022
 

Speakers

Photos of speakers


From top left:
Frank B Hu, Paul W Franks, Marju Orho-Melander, Andrew T Chan, Walter C Willett, Miguel A Martínez-González,
Shilpa Bhupathiraju, Rikard Landberg, Matthias Schulze, Qi Sun, Marta Guasch-Ferré, Karl Michaëlsson,
Clemens Wittenbecher, Clary Clish, Jessica A. Lasky-Su, Liming Liang, Carl Brunius, Mats Jirstrand,
Fredrik Bäckhed, Ann-Sofie Sandberg, Majken K. Jensen, Jordi Merino, Göran Bergström

Program

Read the full program here (pdf)

MONDAY (12 September)

13:30-15:45 Towards Precision Nutrition- Improving Individual and Population Health

Session Chair: Clemens Wittenbecher (Chalmers University of Technology)

Frank B Hu (Harvard T. H. Chan School of Public Health)
: Promises and challenges of precision nutrition in disease prevention and management

Paul W Franks (NovoNordisk Foundation): Clinical deployment of precision medicine for chronic complex diseases – a focus on primary prevention approaches

Marju Orho-Melander (Lund University): The gut microbiome and plasma metabolome in cardiometabolic disease

Andrew T Chan (Massachusetts General Hospital): Leveraging the gut microbiome for precision prevention of cancer

15:45-16:00 Break

16:00-18:00 Healthy dietary patterns – Understanding underlying mechanisms through OMICs approaches

Session Chair: Marta Guasch-Ferré (Harvard T. H. Chan School of Public Health)

Walter C Willett (Harvard T. H. Chan School of Public Health): Nutrition epidemiology provides evidence for improving human and planetary health through healthy dietary patterns

Miguel Ángel Martínez González (University of Navarra): Understanding the health benefits of the Mediterranean diet interventions on cardiometabolic risk prevention through metabolomics profiling

Shilpa Bhupathiraju (Harvard T. H. Chan School of Public Health): The imprint of ethnically diverse dietary patterns on the metabolome

Rikard Landberg (Chalmers University of Technology): OMICs to understand the metabolic benefits of the Nordic diet and its key components

Questions and Answers

18:00-20:00 Poster and networking session

Moderators: Malin Barman (Chalmers University of Technology) and Jordi Merino (Massachusetts General Hospital)

Presentation of selected posters on precision nutrition and OMICs research and infrastructure. Connect with speakers and poster presenters - food and beverages will be available.

TUESDAY (13 September)

8:30-10:45 Deep molecular phenotyping in cohorts and trials - Elucidating the interplay between diet, metabolism, and disease risk

Session chair: Jordi Salas Salvado (Universitat Rovira i Virgili)

Matthias B Schulze (German Institute of Human Nutrition): Deep molecular phenotyping in the EPIC-Potsdam study provides insights into cardiometabolic disease etiology

Qi Sun (Harvard T. H. Chan School of Public Health): The interplay between effects of diet and microbiome on the metabolome

Marta Guasch Ferré (Harvard T. H. Chan School of Public Health): Metabolic signatures of health-relevant foods and their association with cardiometabolic diseases

Karl Michaëlsson (Uppsala University): Deep molecular phenotyping in cohorts - Elucidating the interplay between diet, metabolism, and disease risk

Clemens Wittenbecher (Chalmers University of Technology): Metabolomics profiling generates diet-sensitive candidate biomarkers of cardiometabolic disease risk

Questions and Answers

10:45-11:15 Coffee break

11:15-13:30 Metabolomics applications in nutrition and chronic disease epidemiology- Developing laboratory and statistical methods

Session chair: Ann-Sofie Sandberg (Chalmers University of Technology)

Clary Clish (Broad Institute of MIT and Harvard): Approaches to nontargeted metabolomics and identification of novel compounds associated with diet, disease, and the microbiome

Jessica A Lasky-Su (Brigham and Women's Hospital): Considering exogenous metabolites to maximize understanding in epidemiological studies

Carl Brunius (Chalmers University of Technology): Exploring the Unknown - Metabolite identification and data quality in untargeted metabolomics

Liming Liang (Harvard T. H. Chan School of Public Health): Genome-wide assessments of inflammatory markers and interpretable polygenic risk score for cardiometabolic disease

Mats Jirstrand (Fraunhofer-Chalmers Centre): Metabotyping using dynamic OMICs data

Questions and Answers

13:30-14:30 Lunch

14:30-17:00 Towards Precision Prevention – Utilizing OMICs profiling for targeted disease prevention

Session chair: Jessica Lasky-Su (Brigham and Women's Hospital)

Fredrik Bäckhed (University of Gothenburg): The metabolic role and therapeutic potential of the microbiome in cardiometabolic disease

Ann-Sofie Sandberg (Chalmers University of Technology): Early life exposures to dietary metabolites in relation to allergy development at 12 months of age

Majken K. Jensen (University of Copenhagen): Proteomics approaches in biomarker discovery for chronic diseases of aging 

Jordi Merino (Massachusetts General Hospital): Diabetes prevention in the era of precision nutrition

Göran Bergström (University of Gothenburg): Longitudinal and cross-sectional molecular profiling of cardiac and metabolic disease in substudies of The Swedish CArdioPulmonary bioImage Study (SCAPIS)

Questions and Answers

Rikard Landberg (Chalmers University of Technology): Closing remarks.


Category Conference
Location: Lindholmen Conference Centre, conference hall, Lindholmspiren 5, Navet
Starts: 12 September, 2022, 13:30
Ends: 13 September, 2022, 17:00

Page manager Published: Tue 21 Jun 2022.