Entatic state model complexes optimize the energies of starting and final configuration to enable fast reaction rates (illustrated by the hilly ground). The work demonstrates that the entatic state principle can be used to tune the photochemistry of copper complexes.
(Credit: RWTH Aachen, Sonja Herres-Pawlis)

New methods to analyze molecular dynamics in biology, chemistry and physics

​A recent paper in Nature Chemistry, involving Chalmers guest researcher Jakob Andreasson, explains a key principle behind reaction of metalloenzymes.

In biology, chemistry, and physics, molecular function is strongly dependent on the interaction between structure and dynamics. In processes such as photosynthesis and many types of catalysis, charge transfer reactions between metal ions and their surroundings, and the time scale on which they occur, play a major role. Jakob Andreasson, guest researcher at the Condensed Matter Physics division at Chalmers University of Technology, has together with an International and interdisciplinary team of researchers performed a study where a combination of ultrashort X-ray and laser pulses were used to show how the local binding of copper ions depends on the speed of charge transfer in photochemical reactions. The results of this demanding series of experiments were published earlier this week in Nature Chemistry.

The research project is led by Sonja Herres-Pawlis from the RWTH Aachen University (RWTH),  Michael Rübhausen from the University of Hamburg and Wolfgang Zinth from Munich’s Ludwig Maximilian University.

Read the press release from DESY



Photo: Jakob Andreasson during preparations for an experiment at the AMO instrument at the X-ray Free Electron Laser LCLS at SLAC, Stanford, California. (Jakob Andreasson, private)


Published: Fri 19 Jan 2018. Modified: Mon 22 Jan 2018