Smalltalks "Multiscale X-ray imaging of pharmaceutical dosage forms"

Abstract:

X-ray imaging is an indispensable tool in material science, providing insights on the internal structure and properties of materials. With the continued development of synchrotron facilities, the quality of data that can be extracted continues to improve, facilitating nanoscale imaging with enhanced speed and resolution. This SmallTalk presents a correlative X-ray imaging methodology combining ptychographic X-ray computed nanotomography and scanning small and wide-angle X-ray scattering. This approach enables multiscale characterization of materials spanning from the nano to millimeter scale. To showcase the developed methodology, we demonstrate structural analysis of a pharmaceutical dosage form, linking the nanostructure and micron morphology to the processing conditions and properties of the material.