Development of a consolidated bioprocess for conversion of plant biomass to versatile chemical building blocks
This project aims to create novel bacterial strains for simultaneous degradation of plant biomass and production of versatile chemical building blocks – a so-called consolidated bioprocess. Most efforts in consolidated bioprocessing have focused on the model organisms E. coli and S. cerevisiae, but thus far major breakthroughs are lacking. Neither of these organisms is adapted to degrade the complex carbohydrates present in plant biomass, and as such their genomes require substantial ‘re-wiring’ to be of use in consolidated bioprocessing.
The focus in this project is instead bacteria with innate capabilities to decompose complex biomass and produce useful molecules. The bacteria will be modified through molecular biology to generate strains to convert both forestry- and agricultural waste streams.
- University of Michigan (Academic, USA)
- Norwegian University of Life Sciences (Academic, Norway)
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- Novo Nordisk Fonden (Non Profit, Denmark)
- Swedish Research Council (VR) (Public, Sweden)
- ÅForsk (Non Profit, Sweden)