Container ships are open and thin-walled structures which are subjected to severe stress levels which often result in fatigue damage in many places. The objective with this project is to study the container ship with regard to its design and structure considering fatigue characteristics. In the project, numerous calculations are carried out: hydrodynamics, finite element analysis and advanced fatigue analysis and post-processing. The results aim to propose improvements and changes in structural designs at critical locations, but also to propose a route-planning tool which contributes to increased life in service and reduction in maintenance costs. It should also be able to support and recommend change in heading angle leading to minimised damage caused to the ship in its current sea state.