The overall goal of the NanoDiaBac project is to develop new nanofluidic tools for the
fast identification of bacterial infections and characterization of antibiotic resistance.
The development of the toolbox is based on obtaining coarse-grained sequence
information from individual DNA molecules extracted from bacteria. The molecules
are stretched in nanofluidic channels and visualized with a fluorescence microscope.
Traditional diagnostic techniques are based on bacteria cultivation, time-consuming
process. The NanoDiaBac technique, in contrast, is based on examining a small
number of single DNA molecules, a process which requires only an extremely small
sample. It obviates time-consuming cultivation and reduces diagnostic time to hours
rather than days. Fast diagnosis is beneficial to the patient by facilitating early and
optimal treatment. It is also beneficial to society since it minimizes the spread of
infectious bacteria and antibiotic resistance.
Published: Thu 19 Jul 2018.
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