With energy levels in the few meV range, terahertz frequencies have unique spectroscopic features for monitoring biological molecules. Moreover, due to the low energy level of terahertz radiation (few meV), the interaction with biological matter is non-ionizing and generates very low cell and tissue damage. This enable sensing and sample identification in a direct non-invasive and label-free manner using terahertz waves.
Our research covers basic science on molecular dynamics in the terahertz frequency range in a joint project between University of Gothenburg and Chalmers and the use of THz waves for the identification and sensing of biomolecules to applied research on instrumentation for the pharmaceutical industry together with AstraZeneca Gothenburg.
- V. Lundholm, H. Rodilla, W. Y. Wahlgren, A. Duelli, G. Bourenkov, J. Vukusic, R. Friedman, J. Stake, T. Schneider, and G. Katona, "Terahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein crystal," Structural Dynamics, vol. 2, pp. 054702–13, 2015. Doi: 10.1063/1.4931825.
- J. Cabello-Sanchez, H. Rodilla, V. Drakinskiy, and J. Stake, “Multiline TRL Calibration Standards for S-parameter Measurement of Planar Goubau Lines from 0.75 THz to 1.1 THz,” presented at the 2018 IEEE/MTT-S International Microwave Symposium - IMS, 2018, pp. 879–882. Doi: 10.1109/mwsym.2018.8439138.