Physics and chemistry of nucleic acids
- Course code: FKBT020
- Course higher education credits: 7.5
- Department: CHEMISTRY AND CHEMICAL ENGINEERING
- Graduate school: Bioscience
- Course is normally given: Every third year
- Language: The course will be given in English
DNA, regarding structure, dynamics and interactions in solution. It is a literature course where each participant gives a presentation (2h) of a chapter of the book. Examination is through 1) the oral presentation, 2) weekly assignments dealing with each lecture, and 3) a few broader assignments at the end of the course.
Nitrogen bases, nucleosides, nucleotides. Chemical and enzymatic methods, Sequencing. DNA structure. UV-vis and IR spectroscopy. Theoretical methods. Size and shape of DNA coils. Conformational change. Circular DNA. Interactions with water, ions, dyes, drugs and proteins. Coil-compaction in vitro and packaging in bacteriophages.
Application is made by sending an email to Björn Åkerman
Nucleic Acids. Structures, Properties and Functions.
Bloomfield, V.A., Crothers, D.M., and Tinoco, I.
University Science Books, Sausalito 2000
Björn Åkerman, email: firstname.lastname@example.org , phone: +46 (0)31 772 30 52
Office: Room 5066, Department of Chemical and Biological Engineering, Physical Chemistry, Kemivägen 10