News: Centre SuMo Biomaterials related to Chalmers University of TechnologyThu, 02 Nov 2017 17:32:04 +0100 collisions at a nanoscale<p><b>​​</b></p><p style="font-size:15px"><img class="chalmersPosition-FloatRight" src="/SiteCollectionImages/Centrum/SuMo/Frida%20I%20250.jpg" alt="" style="height:176px;width:155px;margin:5px" /><strong>Hydrophobic surfaces are efficient materials to use for instance for packaging p</strong><strong>urposes. </strong><a href="/en/Staff/Pages/frida-iselau.aspx">Frida Iselau industrial PhD student</a><strong> <span style="font-size:14px"><span style="font-size:14px"><span style="font-size:14px"><span style="font-size:14px">at Chemistry and Chemical Engineering and Kemira/AkzoNobel has been studying the fundamental principles of a technique called “Surface sizing”, a method for creating hydrophobic, and thereby more water resistant, paper materials by applying hydrophobic nanoparticles on the paper surface. </span></span></span></span></strong></p> <p style="font-size:15px"><span style="font-size:14px"><span style="font-size:14px"><span style="font-size:14px"><span style="font-size:14px"></span></span></span></span> <br />What can you tell us about your research and results?</p> <blockquote dir="ltr" style="font-size:14px;margin-right:0px"><p style="font-size:14px"><span style="font-size:14px"><span style="font-size:14px"><img width="228" height="204" class="chalmersPosition-FloatLeft" src="/SiteCollectionImages/Institutioner/KB/Generell/Nyheter/dropletonsurface%20340.png" alt="" style="height:207px;width:223px;margin:5px" /></span>For packaging purposes a paper material needs to be hydrophobic in order to withstand water and moist exposure during transportation and storage. In my research I have shown that it is important to control the colloidal behaviour of the particles in order to get an efficient process and this knowledge can be used for a more knowledge-driven product development in the future. Some parts of my research has already been implemented, both in the particle synthesis process and in the application.</span></p></blockquote> <p>You are an industrial PhD student at Kemira and AkzoNobel. How is that compared to be only in academia?</p> <blockquote dir="ltr" style="margin-right:0px"><p><span style="font-size:14px">I started as an industrial PhD student at AkzoNobel, but two years after I’ve started my PhD studies the Paper Chemicals division at AkzoNobel was divested to the Finnish chemical company Kemira! Fortunately Kemira found my PhD project interesting and it was no problem for me to continue my project. Actually the global R&amp;D Manager Heidi Fagerholm at Kemira is engaged in my project as a steering group member. So I’m not a typical industry PhD student, but the main difference when I compare with only academia is the advantage to have two work places with great competences in different areas. At Chalmers I have access to advanced instrumentation and very skilled people within chemistry and at the company I have access to more specialized equipment and the experience from my colleagues within my research field. </span>  </p></blockquote> <p>How has your collaboration with SuMo BIOMATERIALS been? What help have you gotten from the centre?</p> <blockquote dir="ltr" style="font-size:14px;margin-right:0px"><p style="font-size:14px"><span style="font-size:14px"><a href="/en/staff/Pages/Romain-Bordes.aspx">Romain Bordes </a>has been my supervisor since 2014. He has been very supporting and a great driving force for my project. My main collaborations have been with <a href="/en/staff/Pages/Aleksandar-Matic.aspx">Aleksandar Matic</a> (Chalmers), <a href="/en/staff/Pages/Tuan-Phan-Xuan.aspx">Tuan Phan Xuan</a> (Chalmers) and Mark Nicholas (AstraZeneca). Aleksandar, Tuan and I have two publications together and their expertise within scattering have contributed much to my project. Mark Nicholas is an expert in ToF-SIMS and we have utilized this technique to reveal how the particles are distributed on and in a paper sheet and we have shown that this correlates to the degree of hydrophobization. Another interesting interaction was with StoraEnso. Chris Bonnerup was the opponent of my Licentiate Thesis. Moreover I have had collaborations with Annika Altskär and Erich Schuster and the SuMo seminars and conferences have been very rewarding as well. </span></p></blockquote> <p>What are your plans for after your thesis defence?</p> <blockquote dir="ltr" style="font-size:14px;margin-right:0px"><p style="font-size:14px"><span style="font-size:14px">After the defence I will stay at Chalmers for a couple of months, finalize some manuscripts. After that I don’t know, if I want to continue within Kemira I would have to move to Helsinki but as for now I would prefer to stay in the Göteborg area. </span></p> <p style="font-size:14px"><span style="font-size:14px"></span> </p></blockquote> <p dir="ltr" style="font-size:14px"><span style="font-size:14px">Image: Kemira</span> </p>Tue, 24 Oct 2017 00:00:00 +0200 gives a deeper view into cavities<p><b>​Charlotte Hamngren Blomqvist, PhD at the department of Physics active within SuMo Biomaterials, recently defended her PhD- thesis on 3D-imaging of Silica Hydro gels.</b></p><strong>​</strong><span style="background-color:initial"><strong>Hello Charlotte! You have been studying methods for analysing porous materials. What did you find?</strong></span><div>In my thesis I mainly look at three things that electron tomography, 3D-imaging at a nano scale in transmission electron microscopy, can be used for.</div> <div>One area is imaging of irregular porous structures in 3D, which makes quantification of the structure possible. This isn’t possible in 2D. We can now describe the porous structure in quantitative terms instead of only using images. We have also characterised the material by showing the inter-connectivity of the pores and also the accessible fraction of the pore volume.</div> <div>My research is also contributing to the possibility to validate the different mathematical models that are used to understand exactly which mechanism that dominates the process of gelation. </div> <div>My thesis also shows how we can model fluids flowing through the gel locally on the nano scale in 3D. This enables us to draw conclusions about the permeability in different parts within the material. What’s new here is that the structure that is used for the modelling of the flow is the very same as the structure detected experimentally in 3D by electron tomography.<br /><br /></div> <div><strong>Why is it important to be able to determine the structure of porous materials?</strong></div> <div>Porous materials are used for many different purposes in our daily life. To be able to understand a material and its characteristics basically, for example ability to transport fluid or an active substance, we have to investigate its structure.<br /><br /></div> <div><strong>Is it a new thing to use electron microscopy for this purpose? And if that is the case, will the thesis have impact on how porous materials will be explored in the future?</strong></div> <div>What’s new is to use electron tomography for 3D-imaging of soft and porous materials with the two focus areas mass transport simulation directly in the structure and modelling studies of gelation mechanisms. 3D-imaging as a concept is usable and desirable when imaging porous materials, since a 2D-image often gives a misleading impression of the material.</div> <div>I certainly hope that my research will have impact! 3D-imaging of porous materials at the nano scale could potentially be of use in a number of fields of current interest such as medical technology and pharmaceutical technology, packaging materials, health care, food science, tissue engineering, catalysis, development of batteries, fuel cells and solar cells.<br /><br /></div> <div><strong>What will you do now when your PhD studies are over?</strong></div> <div>I want to continue to research, either in the industry or the academy. This far I have mainly been working with fundamental research. Now I want to move towards more applied research. It is appealing to explore and develop something that in the long run contributes to a more sustainable society or that increases the life quality for those in need.<br /><br /></div> <div><strong>How do you experience working with SuMo Biomaterials? </strong></div> <div>The SuMo-collaboration has given me much. The centre has provided an important network for our interdisciplinary collaborations, both within the academy and with the industry. AkzoNobel has been my main industrial partner and the collaboration has been very rewarding. It has also been interesting to take part of so many other researcher’s work and see their progress over many years.</div> <div><br /></div> <div><div><em><a href="/en/centres/sumo/Pages/default.aspx">SuMo Biomaterials​</a> in short</em></div> <div><em>SuMo Biomaterials is a Vinnova (Swedish government agency) supported centre and research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.</em></div> <div><em> </em></div> <div><em>The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goal to generate added value for industry, academia and society.</em></div></div> <div><br /></div> <div><br /></div> Mon, 06 Mar 2017 00:00:00 +0100 behaviour of cells<p><b>​​To understand how our body works it is very important to understand the nature of the cells and why they behave like they do. Adele Khavari at the Department of Chemistry and Chemical Engineering presents her PhD thesis where she has investigated how cells interact in different microenvironments.</b></p><p><img class="chalmersPosition-FloatRight" src="/SiteCollectionImages/Centrum/SuMo/Adele_Khavari.jpg" alt="" style="height:164px;width:125px;margin:5px 10px" /></p> <p><strong>What forces are interacting with the cells?<br /></strong>Cells are exposed to diverse forces including compression and tension from the neighbouring cells, fluid shear stress, hydrostatic and osmotic pressure, and the stiffness of the extracellular matrix.  <br /> <br /><strong>What is mechanotransduction?</strong><br />Cells sense the mechanical stimuli from their environments, and then convert them to biochemical responses through a process called mechanotransduction. In mechanotransduction there are dozens of mechanisms. Most of these interactions have similar underlying principle. Stress or strain typically induces conformational and/or organizational changes to the sensing unit, which can be a protein or an ion channel. Their structural changes regulate binding organization, or ion flow, which ultimately influence cell function. <br /> <br /><strong>You study cancer cells, benign and metastatic in this project. Does your work contribute to cancer research?<br /></strong>Definitely, we don’t know what the most important mechanical driving force for metastasis is, however, we know that the cells and the environment mechanically change a lot in the case of cancer. One of my work contribution is to design a device to be used in cancer diagnosis and also to understand the role of mechanics in the metastasis. <br /> <br /><strong>Describe this micro world in which the cells interact in your thesis. Why did you use polymer gels for your research? <br /></strong>As I mentioned before cells are exposed to different forces and one of them is the stiffness of the extracellular matrix. In my thesis I have used different polymer gels to create mechanically relevant environments for the cells. By doing this we are able to understand how the mechanics of the microenvironment influence the cell function.  <br /> <br /><em><strong>What did you find about the interaction between the cells and the polymer gels? <br /></strong></em>To summarize, I learned that the mechanical properties of the gel (extracellular matrix) influence both growth and migration. In the case of metastatic breast cancer my experiment showed that higher mechanical properties of the gel induce more growth and the cells generate more power. <br /> <br /><strong>How has your cooperation with SuMo been working for you? <br /></strong>I think it is always good to interact with scientist from both industry and academy, SuMo provide such an environment.  </p>Thu, 08 Dec 2016 00:00:00 +0100 Larsson gets pedagogical prize<p><b>​Anette Larsson, professor in Pharmaceutical Technology and director of the center SuMo BIOMATERIALS, gets the Chalmers pedagogical prize.</b></p><div>Motivation: For her systematic work with reforming a laboratory experiment in the advanced course Galenical Pharmaceutics. To help the students reach a better understanding of the purpose of the laboratory experiment, <a href="/sv/personal/redigera/Sidor/anette-larsson.aspx">Anette Larsson</a> has created a clear learning sequense by put in interactive lectures before and after the experiments. These lectures put the experiment in its context and support a deeper learning. This learning sequense gives the students a better understanding of the purpose of the experiment and the developed a greater understanding of the key concepts connected to the experiment.​</div> <em>​</em><div><em></em><span><em>What does the prize mean to you?</em></span><div>This means a lot to me. Teaching is important. It is one of the main tasks a university has! So I became very happy when I got the decision.</div> <div><br /></div> <div><em>What makes you a good teacher?</em></div> <div>I am not even sure that I am a good teacher - I don’t know all the theories about learning and teaching, and I always finds things that I want to improve and so on. But I am sure about one thing - I WANT to teach in good way and I WANT the students to learn. Knowledge is very important to me. With knowledge you can explore a new world. To share knowledge and give the students new ways to explore and explain the world is like giving them a gift, a gift that they can take with them for the rest of their lives. To see in their eyes when they suddenly realize that they have understood something difficult. It is such a relief for them. That is something special! It is a direct feedback as a teacher and I get an enormous satisfaction from these small aha- experiences.</div> <div><br /></div> <div><em>What is important to think about to be a successful teacher? </em></div> <div>There are many things!</div> <div>I want to create a hunger for learning in the students, sometimes even if they, in the beginning, did not know that they had an interest in that subject. My strategy is that I want to make them curious, so that they get this hunger for knowledge.</div> <div><br /></div> <div>To facilitate that it is important to give the students as good possibilities to learn as possible. My hypothesis is that active students learn more and therefore I try to create better circumstances for learning on a deeper level by keeping them busy: they must answer questions, discuss in pair and report back, write down things they find difficult and reflect on one subject from many different points of view during the lectures. I also try to learn as many of their names as possible, to show them respect and that they are important for me and that I am interested in hearing their opinions. I also try to inspire them and show that this, this knowledge, this small detail, is really important for me and fascinates me a lot and that I want to share my fascination with them. Last but not least, it is important for me to make difficult things more comprehensible by taking examples from their real lives and I very often (almost to ever lecture) bring stuff with me to the lessons to illustrate abstract things. Like how one make granulations, tablets, coat tablets etc or make abstract theories more visible by for example comparing plastic deformation with fragmentation. Do you know how efficient it is to illustrate fragmentation with a piece of rye bread on an overhead projects? It is quite much cleaning afterwards, but it is worth it!</div> <div><br /></div> <div><em>You also received a prize from the pharmacist students' council at the Sahlgrenska Academy. Have you done anything special this year when it comes to education?</em></div> <div>The prizes are quite different. The prize from Sahlgrenska Academy was a price from the students. They had selected me as the best teacher in their pharmacy education, which I am extremely honored of.  Maybe I got that price due to that I shared my enthusiasm and willingness to teach, and that I have their learning in focus. </div> <div>The prize from Chalmers is more that I have been reflecting over that sometimes the lab exercises we have in our courses are hanging like clouds in the sky without clear connections for the students to the rest of the courses. I have developed a method, the Babushka concept, in collaboration with my former PhD-student <a href="/en/staff/Pages/sofie-gardebjer.aspx">Sofie Gårdebjer</a>, to put a lab exercise in a pharmacy course in an integrated instructional unit. This means that we discuss from a wide perspective, where the students have knowledge (in this case about bioavailability), to more deeper things (solid dispersions and characterization of them) at a lecture before the lab exercise. This makes the students very well prepared and they understand why they do things at the lab and can discuss and ask deeper questions during the exercise. After the lab we sum up the learnings by going back from small detailed thing and put this knowledge back in their wider contexts. We also have written a pedagogical manuscript on this way to organize the teaching around an exercise at a laboratory. We did this in collaboration with the professor in pedagogics, <a href="">Tom Adawi​</a>. </div> <div><br /></div></div> <div><a href="/en/departments/physics/news/Pages/Pedagogical-prize-to-Ulf-Gran.aspx">Ulf Gran​</a>, Associate Professor at the Departmetn of Physics and <a href="/en/staff/Pages/mikael-odenberger.aspx">Mikael Odenberger​</a>, Researcher and Teacher at the Department of Energy and Environment, have also been awarded the pedagogical prize 2016. <br /></div>Fri, 30 Sep 2016 00:00:00 +0200 students in research project<p><b>​In their bachelor thesis students from Chemical Engineering with Engineering Physics and Bioengineering programs, collaborate in a research project.</b></p>​<span>The goal is to test and develop a hydrogel with the ability to couple antennas and the human body, as well as acting as the cooling agent necessary during hyper thermia treatment of cancer, compared to the currently used water bolus. the project is led by <a href="/sv/personal/Sidor/hana-dobsicek-trefna.aspx">Hana Dobsicek Trefna</a> at Dept. of Signals and Systems, active within the centre <a href="/en/departments/e2/centres/Chase/Pages/default.aspx">Chase </a>and <a href="/en/Staff/Pages/anna-strom.aspx">Anna Ström</a> at Dept. of Chemistry and Chemical Engineering and active within the centre  <a href="/en/centres/sumo/Pages/default.aspx">SuMo BIOMATERIALS</a>.</span><span>​</span>Fri, 13 May 2016 00:00:00 +0200 packaging with less material<p><b>​Much of the food sold in our grocery stores are packaged to avoid that substances like oxygen get in contact with the food and decompose it. It is of great importance to know which parameters that decide the permeability of the material. Within the competence center SuMo BIOMATERIALS at Chalmers researchers are developing materials with optimized properties.​​</b></p><a href="/en/Staff/Pages/sofie-gardebjer.aspx">​<span>Sofie Gårdebjer</span></a><span>, PhD at SuMo and Chemistry and Chemical Engineering recently defended her thesis &quot;Mass Transport Through Polymer Films: The Importance of Interfaces and Compatibility&quot; where she demonstrates techniques to create functional barriers, while at the same time reducing material usage, which is desirable since packaging contributes to a significant amount of our waste.</span> <p class="MsoNormal"><b><span lang="EN-US">​</span></b></p> <p class="MsoNormal"><b><span lang="EN-US">Describe the material that you examined</span></b></p> <p class="MsoNormal"><span lang="EN-US">A composite materials may consist of a matrix polymer and a filler. When these are combined it is desired that the fillers are dispersed as much as possible, especially if you have a impermeable filler with the purpose of reducing the permeability. The better the filler is dispersed into the matrix the harder for the molecules to get through the barrier. Another way of combining materials is by creating laminates, i.e. layer structures. Also in this case it is important to have a good compatibility between the materials to get a good barrier.<br /></span><b><span lang="EN-US"></span></b></p> <p class="MsoNormal"><b><span lang="EN-US">Tell us about your results</span></b></p> <img width="2592" height="3456" class="chalmersPosition-FloatRight" src="/SiteCollectionImages/Centrum/SuMo/SofieGardebjer2.jpg" alt="" style="height:198px;width:148px;margin:5px" /><span lang="EN-US">It is not a simple task to create a good barrier. There are many factors that are important when creating a functional barrier material. Our results show, for example, that when the filler is well dispersed in a composite material, it can results in a porous material. Porous materials have lower barrier properties than a non-porous. We also show that we can improve the barrier properties of the laminates when the polymer chains are in order at the interface, which acts as a barrier for transported molecules.</span><p class="MsoNormal"><b><span lang="EN-US"></span></b> </p> <p class="MsoNormal"><b><span lang="EN-US">How interested is the industry of your research? </span></b></p> <p class="MsoNormal"><span lang="EN-US">Since I'm in SuMo Biomaterials I get my research questions directly from the industry. There is also a general interest in creating as good barriers as possible from as little material as possible. Another thing is that you may not always want a completely impermeable barrier. For example, in a wound care product you don’t want to have any accumulation of water on the skin, but you want to adsorb wound exudate. Also in this case it is important to know the structure of the material and its barrier properties.</span></p> <p class="MsoNormal"><b><span lang="EN-US"></span></b> </p> <p class="MsoNormal"><b><span lang="EN-US">Has it been beneficial for you to be part of SuMo BIOMATERIALS?</span></b></p> <p class="MsoNormal"><span lang="EN-US">I think it has been very valuable to be part of Sumo. It is motivating to know that what I do is of interest to someone else too. It is also inspiring to see so many dedicated people who are interested in what I do. I have had good relationships with several of the companies involved, which I have learned a lot from. Another positive thing is that we get a lot of training in communication, since we must be able to explain what it is we do in an understandable way for people who are not so familiar with the topic but still are interested.</span></p> <p class="MsoNormal"><b><span lang="EN-US"></span></b> </p> <p class="MsoNormal"><a href="/sv/personal/redigera/Sidor/anette-larsson.aspx"><b><span lang="EN-US">An</span></b><b><span lang="EN-US">ette</span></b><b><span lang="EN-US"> Larsson</span></b></a><b><span lang="EN-US">, you have been Sofie’s supervisor during her time as a PhD student as well as being direktor of SuMo BIOMATERIALS. How does her thesis connect to SuMo’s mission?</span></b></p> <p class="MsoNormal"><span lang="EN-US">This project is close to the focus question of SuMo, molecular transport in materials and how it is dependent on the structure of the materials. It has contributed to SuMo by giving new insights in how the properties of the interfaces in a material influence the molecular transport. The knowledge platform can inspire Swedish companies to develop more efficient package materials. At the same time one should remember as stated by Lawrence Nielsen, 1967: “Permeability, especially of liquids, is extremely complex, and many different types of behavior can be expected.”  Therefore, SuMo will continue to develop knowledge within this area.​​</span></p> <p class="MsoNormal"> </p> <p class="MsoNormal"><a href=""><span lang="EN-US"><span>Sofie </span></span><span lang="EN-US"><span>Går</span></span><span>debjer's</span><span> Doctoral thesis</span></a></p> <p class="MsoNormal"><span lang="EN-US"><br /></span><span lang="EN-US">Text: Mats </span><span lang="EN-US">Tib</span><span>orn</span><span></span></p> <p class="MsoNormal"><span>Photo: Mats Tiborn and Johanna Andersson </span></p> ​ <div><div><em>SuMo Biomaterials in short</em></div> <div><em>SuMo Biomaterials is a Vinnova (Swedish government agency) supported research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.</em></div> <div><em> </em></div> <div><em>The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goal to generate added value for industry, academia and society.</em></div></div> <div><br /></div> ​Thu, 03 Mar 2016 00:00:00 +0100 materials for drug delivery<p><b>​Resistant bacteria is a growing problem in the whole world. The reason is that antibiotics often is used more often than necessary. In infected wounds, especially chronic wounds which are common for patients with diseases such as diabetes where the blood circulation is poor, antibiotics is used.</b></p><p>​<img width="200" height="303" src="/SiteCollectionImages/Institutioner/KB/Generell/Nyheter/Marina/Marina%202015.200.jpg" class="chalmersPosition-FloatLeft" alt="" style="height:173px;width:115px;margin:5px 10px" />Marina Craig, who recently finished her industrial PhD studies within SuMo Biomaterials in a cooperation between Chemistry and chemical engineering at Chalmers and Mölnlycke Health Care, saw a possibility to develop a material that could lead to reduced use of antibiotics by letting the infection itself distribute the antibiotics.</p> <p><br />The material Marina Craig has been studying is a nano film that works as a barrier between bio active substances, for example drugs, and the bacteria’s degradation enzymes, protease. The inside of the barrier holds drugs suited to kill bacteria. When the bacteria’s protease degrades the barrier the bacteria is exposed to drug and it dies. </p> <p><br /><strong>Tell us about the material</strong><br />It is a nano film made of polypeptides. The thin film can be used as a surface around a very small capsule with drugs for one or more bacteria. The film is degraded by the bacteria’s protease. The protease I<img src="/SiteCollectionImages/Institutioner/KB/Generell/Nyheter/Marina/bakterier350.jpg" alt="Microcapsules loaded with antimicrobial drugs assembled using template assisted assembly and layer-by layer technique." class="chalmersPosition-FloatRight" style="height:175px;width:200px;margin:10px" /> have focused on are specific and unique for each kind of bacterial strain in that matter that they only degrade specific kinds of surfaces. I put a lot of effort in finding the right kind of protease and the right kind of polypeptide that are suited for fighting two kinds of bacteria that are causing disease, Staphylococcus aureus and Pseudomonas aeruginosa. Since the degradation of the barrier depends on the amount of protease surrounding it, the amount of exposed drug will also be in proportion to the bacteria causing disease. </p> <p><br />Polypeptides already exist and is no discovery in itself. What I have done is finding a new way of using them and show a connection that no one has seen before when it comes to designing barriers to suit the protease.</p> <p><br /><strong>Why does it mainly suit treatment of chronic wounds? </strong><br />That’s where the biggest problems lie. Those who have an underlying problem like for example diabetes also have a higher risk of having problems with chronic wounds because of poor blood circulation. The idea is that as much as possible is treated locally, instead of exposing the whole body to drugs when you have an infection. </p> <p><br /><strong>What would a finished product look like?</strong><br />That is not part of the study, but it could be used in bandages, gel or crème. I haven’t looked into the product, but instead focused on getting the system to work. </p> <p><br /><strong>What’s the next step?</strong><br />We’re not working with it at the moment because of problems with the patenting, but who knows, perhaps it becomes real in the future. At least now the knowledge is out there.</p> <p><br /><strong>What benefit do you find in working within SuMo BIOMATERIALS? </strong><br />It has been really great since I work alone and don’t belong to a group. The SuMo members were always there to help. Everyone wanted to help and I tried to help others when I could. It is a well-functioning centre in which we exchange knowledge and favours. </p> <div> </div> <div>Marina Craigs' <a href="">Doctoral thesis: Bacteria-responsive materials for drug delivery</a></div> <div> </div> <div>Text: Mats Tiborn</div> <div> </div> <div> </div> <div><em>SuMo BIOMATERIALS in short</em><br /><em>SuMo Biomaterials is a Vinnova (Swedish government agency) supported research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.</em><br /><em> </em><br /><em>The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goal to generate added value for industry, academia and society.</em></div> <div> </div> <p> </p>Tue, 17 Nov 2015 00:00:00 +0100 weight important when optimising drug release<p><b>​​​</b></p><p>To enable a drug to get absorbed by the body in the proper speed and the proper amount it is possible to spray a liquid on small drug cores which will form a membrane that the drug must get through before it reaches the body. The liquid that is creating the membrane consists of modified celluloses and how quick a drug <img class="chalmersPosition-FloatRight" src="/SiteCollectionImages/Centrum/SuMo/" alt="" style="height:168px;width:127px;margin:10px" />is released depends on the characteristics of the membrane. In her thesis, Helene Andersson, industrial PhD at Chalmers and the institute SP Food and Bioscience, analyses two types of cellulose derivates, i.e. chemically modified cellulose, and looks into how their molecular weights are affecting the characteristic microstructures of the membrane and thus the ability to transport the drug. Knowledge about this may lead to membranes that help the drugs to be released in the body at the right time and amount.  </p> <p>The two cellulose derivate she has looked into are called ethyl cellulose and hydroxypropyl cellulose. Mixed together these two polymers tend to phase-separate when spray-coated on small pellets, which creates membranes with unique characteristics. For instance, leakage of the water-soluble hydroxypropyl cellulose can lead to microscopic pores forming in the membrane when it is exposed to water. The amount and shape of the pores themselves depend on the phase-separated structure, which in turn is influenced by the molecular weight of the two polymers. The thesis also deals with aspects such as how to shape the membrane microstructures using rapid drying. </p> <p><br /><strong>What are the results in a larger perspective as you see it?</strong><br />We have shown that the molecular weight can be used as a tool to create a range of new microstructures with specific mass transport properties. On the other hand, different systems, i.e. different molecular weight combinations, respond differently to manufacturing conditions. Even though you know the behaviour of one system, you cannot necessarily predict the behaviour of another one. <br /><br /><strong>How unique/new is this?</strong><br />I think that in general, the molecular weights of polymers have been thought of mainly as a tool to modify the viscosity of polymer solutions or mechanical properties of films and other products, not mainly for designing microstructures. For this system and its application it is very unique and, to my knowledge, for polymer blend films in general I have not seen any work that focuses on structure control by phase separation utilizing both the molecular weight and manufacturing conditions.</p> <p><br /><strong>What is the impact/benefit for society?</strong><br />Hopefully my results will increase peoples’ awareness when designing new materials and products, what tools they can work with and what impact specific polymer properties can have. My hope is also that the pharmaceutical industry can make use of this knowledge to effectively create better formulations with desired properties.</p> <p><br /><strong>What is the benefit of working within a VINNOVA VINN Excellence centre as SuMo Biomaterials?</strong><br />You get valuable feedback from both scientists from the academy and the industry throughout your project. I have been given the opportunity to work closely with people from various scientific disciplines and do my work in different environments, both at SP, the company labs and at Chalmers. It makes you reflect on your research from different angles. The spirit in SuMo is also very relaxing and open, while at the same time the people are passionate, driven and very skilled within their fields. Overall, it has been greatly rewarding to have so many amazing people and personalities showing interest in my research. </p> <div> </div> <div>More info on Helene Anderssons' <a href="">Doctoral thesis</a></div> <div> </div> <div>Text: Mats Tiborn</div> <div> </div> <div> </div> <div><em>SuMo Biomaterials in short</em><br /><em>SuMo Biomaterials is a Vinnova (Swedish government agency) supported research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.</em><br /><em> </em><br /><em>The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goal to generate added value for industry, academia and society.</em></div>Wed, 11 Nov 2015 00:00:00 +0100 method enables prediction of the characteristics of viscoelastic fluids<p><b></b></p><p>​​<img class="chalmersPosition-FloatRight" alt="Magda Nyström’s method lets you predict the extensional viscosity of viscoelastic fluids" src="/SiteCollectionImages/Centrum/SuMo/SIK175.jpg" style="height:228px;width:175px;margin:10px" />It is important to know a material’s extensional properties in the production of plastics, polymers and food. These properties are determining factors when it comes to how easy a fluid is to swallow or how porous a bread can be, but it is also essential in the production of foam and plastic film. Through both experiments and simulation, PhD Magda Nyström, until recent industrial PhD Student at SP Food and Bioscience and Chalmers, has developed a method that predicts the extensional viscosity of viscoelastic fluids. The method predicts the behaviour of the material in a way that most commercially available instruments cannot do.<br /><br /><strong>What are the results in a larger perspective?</strong><br />The Hyperbolic Contraction Flow method has been further developed and established which makes it possible to determine extensional viscosity also for medium viscosity fluids such as plastic melts, foods, pulp dispersions and biological fluids. These results can be used to predict the behaviour of e.g. plastics in processing, foods during swallowing and flow in biological processes, from the measured material properties. <br /><br /><strong>What is the impact/benefit for society?</strong><br />The knowledge of a material’s extensional viscosity can be used in process optimisation and product development to achieve a product of high quality and desired properties. The use of mathematical models can also make the material testing much more efficient. Another unexpected result is the use of a hyperbolical shape when adjusting pipe diameters in process pipes. Whenever pumping a thick, viscoelastic fluid you can save lots of energy by making the transition from one pipe diameter to another hyperbolically shaped, rather than abrupt or funnel shaped!  </p> <div><strong>How will the research proceed?</strong><br />The Hyperbolic Contraction Flow method will be further developed and used to characterize fluid properties in a range of fields. </div> <div> </div> <div>Magda Nyström conducted her research in the Structure and Material Design research group, which is part of the SP Food and Bioscience (SP FB) located in Gothenburg, led by Mats Stading who is also Adjunct Professor at Polymeric Materials and Composites. SP FB has a close experimental cooperation with SuMo BIOMATERIALS.</div> <div> </div> <div>For more information please contact <a href="">Mats Stading.</a><br /></div>Thu, 29 Oct 2015 00:00:00 +0100 liquid transport studies from Chalmers to Harvard<p><b></b></p><p>​<img class="chalmersPosition-FloatLeft" src="/SiteCollectionImages/Centrum/SuMo/Christoffer%20A.jpg" alt="" style="height:163px;width:125px;margin:5px" /></p> <p> </p> <p> Christoffer Abrahamsson has defended his thesis at Chalmers. The PhD was performed within the framework of the VINN Excellence centre SuMo Biomaterials and focusing on “Microstructure and liquid mass transport control in nanocomposite materials”. In autumn 2015, Christoffer will start a Postdoc at Harvard in Professor George Whiteside’s group dealing with the development of “Zero-cost sensors”. </p> <div><br /><strong>What has the main focus of your research project been?</strong></div> <div>We have been trying to find out how characteristics in porous materials microstructure affect how liquids move through the pores.</div> <div> </div> <div><strong>What is the benefit of working within a VINNOVA VINN Excellence centre such as SuMo Biomaterials?</strong></div> <div>It has been amazing to solve research questions with experienced and talented people from both academia and industry. As a PhD student the feedback from the industry has made me confident that my work has relevance also in an industrial setting.</div> <div> </div> <div><strong>What are the results in a larger perspective as you see it?</strong><br />Our findings can be used to understand and better predict how changes in the microstructure affect the movement of liquids and dissolved substances through porous materials. In the future these results can be utilized in computer based design of materials prior to their synthesizing in the lab. Computer based design of new materials have potential to reduce the time and cost of development of the next generation of porous materials.    </div> <div> </div> <div><strong>How unique/new is this?</strong><br />Very new, few research centres have tried anything similar and no one has done it for wet materials with low volume fraction solid substance.</div> <div> </div> <div><strong>What is the impact/benefit for society?</strong><br />A more cost effective material design process could produce more innovations for less money, which will strengthen the competitiveness of company and research environments in Sweden.</div> <div> <img class="chalmersPosition-FloatRight" alt="Flow of water in a simulated silica structure. " src="/SiteCollectionImages/Centrum/SuMo/350.jpg" style="height:165px;width:216px;margin:5px" /></div> <div><strong>How will your research activities proceed?</strong><br />I will continue my work on liquid movement in porous materials as a postdoc. This time the focus will be on paper based microfluidics and its use in extremely cheap medical diagnostic devices ('Zero cost'). These devices use the capillary action of paper to transport liquids in the device to make advanced analytical assays. </div> <div>I am looking forward to do this work in Professor George Whiteside’s group at Harvard University, Boston, USA.<br /><br /> <br /><strong>Facts</strong><br />Christoffer defended his thesis at Chalmers on the 28th of August 2015.  <br />His thesis is available at: <a href=""></a></div> <div> </div> <div>More about Harvard Professor George Whiteside’s work on creating cheap, simple and robust devices for diagnosing disease in the developing world in ScienceNews (2014) can be found at:<br /><a href=";context=189321">;context=189321</a></div> <div><br />--------------------------------------------------------------<br /><strong>SuMo Biomaterials in Short </strong><br />SuMo Biomaterials is a Vinnova (Swedish government agency) supported research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.<br /> <br />The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goal to generate added value for industry, academia and society.</div> <div> </div>Wed, 23 Sep 2015 00:00:00 +0200 shows how particles and fluids are spread in porous materials<p><b>​SuMo Biomaterials is a VINN Excellence centre at Chalmers with 35 research groups, seven participating companies and the institute SP Food and Bioscience. The centre is funded equally by Vinnova, the industry and Chalmers. The mathematicians Alexei Heintz and Tobias Gebäck take part with a computer program for simulations of transport processes in different materials.</b></p><img width="250" height="185" class="chalmersPosition-FloatLeft" alt="Diffusion through a porous cellulosa film" src="/SiteCollectionImages/Institutioner/MV/Nyheter/cellulosa250.png" style="margin:5px" />Some years ago, the then director of SuMo Biomaterials, Magnus Nydén, came and asked if the Division of Mathematics was interested in creating a computer program for transport processes. Alexei Heintz and Tobias Gebäck visited industry people in place to try to figure out what it was that they wanted. They soon found out that not the same language was spoken in industry as in academy. The time scale for when things were wanted was also different and the problems that were to be solved were often very complicated. There was no shortage of data, the amounts were rather on the verge of the computational power of the computers, and it took some time before data that were possible to use were accumulated. But now, there is a useable program available for all in the centre, including the companies.<br /><br />The program which has been named Gesualdo simulates diffusion and flows in arbitrary porous structures, from a mathematical point of view arbitrary geometries. Alexei gives an example of when a drug tablet is sprayed with different polymeric mixtures so that the substance will spread slower in the body, you then want to know how long time it takes depending on the structure of the mixture. The materials can for example be cellulose based, polymeric, consist of foam or be structured of silica particles, and it is possible to simulate fluids, particles or particles in fluids. The program uses Lattice Boltzmann equations brought from kinetic theory. During the journey, new mathematical problems have arisen and some physical questions have not been known before, as how some processes happen at a microscopic level. Then it has been necessary to create new theory from the basis within the area of homogenization theory.<br /><br /><img width="170" height="220" class="chalmersPosition-FloatRight" alt="Alexei Heintz" src="/SiteCollectionImages/Institutioner/MV/Nyheter/heintzintervju.jpg" style="margin:5px" />– Certain issues are located in the borderland between mathematics, theoretical physics and physical chemistry, but are hard to get a grip on from all areas. The applied mathematics sometimes needs more abstract mathematics than what the abstract mathematics itself needs, because you do not know what equations you can apply to the problem. You cannot find the answer in the literature but must redo every step to find that which you are interested in. <br /><br />Mathematical statistics is also a part of SuMo Biomaterials. Mats Rudemo has been a member of its board from the start, and together with Aila Särkkä and PhD students they have mainly devoted themselves to image analysis. It is about interpreting experimental two- and three dimensional images with a lot of noise in them, and about simulating three dimensional structures. SuMo Biomaterials now has 1.5 years left of the research centre's period of ten years. The continuation of the mathematical statistics part is secured through a grant from SSF.<br /><br />– There are big plans also for our computer program to continue to develop, so that it can simulate more complicated physical processes with interaction between particles and materials. There is a new postdoc coming in October, it really is way too much work to develop these kind of things on just two persons so it is a welcomed addition. The companies want to continue to use the program also after SuMo Biomaterials has come to an end but the funding is not solved yet. It takes longer time when working together with the industry compared to when researching by oneself and it is a longer way before you reach results, but you also get very much encouragement, the social situation is totally different, so it has been both challenging and fun to work with this, Alexei concludes.<br /><br /><br /><strong>Text and photo</strong>: Setta Aspström<br /><strong>Picture</strong>: Diffusion through a porous cellulosa film that is added to drug pellets, created with help from GesualdoMon, 14 Sep 2015 15:00:00 +0200 thesis opportunity<p><b>The Influence of water retaining additives on the drying process of water borne paint will be studied in an upcoming master project hosted by SP Food and Bioscience together with AkzoNobel. The project will be performed within the framework of SuMo Biomaterials. The master thesis position is now open for applications and interested candidates can apply for the position.</b></p><p><span style="font-size:14px">​Project objectives</span><br />This project will systematically evaluate the drying process of paint via a classical and the alternative FRAP method, more specifically:<br />•   Try to find correlation between the water mobility in the paint, measured by FRAP, and the drying time measured  <br />     with paint application tests.with paint application tests.<br />•   Investigate the influence of different water retaining ingredients in the paint on the drying time.</p> <div style="font-size:14px"> </div> <div><span style="font-size:14px">Background</span><br />When applying water born paint at hot conditions and on water absorbing substrates result in too short drying time. The most significant negative effect is that the water loss is so rapid that the paint film begins to set and when one pass of the roller is overlapped with the previous one, it can result in color and textural differences, which affect the aesthetics of the paint. The painted surface will appear very non uniform in color or gloss. The problem is more severe for exterior paints, but the problem exists in interior applications as well.<br />We have developed a method to determine the drying time of paint on a porous surface. The preliminary results indicate that the loss of water into the substrate has a large influence on the drying speed. We have also seen indications that the drying time differ from one paint formulation to another. <br />In a previous study we have shown that a microscopy based technique, Fluorescence Recovery After Photobleaching, is a promising alternative method to study water mobility in paint and to quantify the drying time of paint. </div> <div style="font-size:14px"> </div> <div><span style="font-size:14px">The work will include </span><br />Literature study, Preparation of water borne paint in lab quantities, Evaluation of drying time on paint samples by application tests, FRAP measurements on paint samples, Evaluation and interpretation of results, and Writing of a report</div> <div> </div> <div>The project will be carried out partly at the Institute SP Food and Bioscience in Göteborg, where the student will get introduced to the state-of-the-art microscopy set-up, and partly at Akzo Nobel in Stenungsund where the paint preparation and paint application testing will be done. </div> <div> </div> <div>The project will be connected to SuMo Biomaterials VINN Excellence centre:  <a href="/sumo"></a></div> <div> </div> <div>Project Duration: 6 months, starting earliest September 2015</div> <div> </div> <div><div><strong>Contact persons</strong><br />Akzo Nobel  -  Leif Karlson<br /><a href=""></a></div> <div> </div> <div>SP   -  Erich Schuster<br /><a href=""></a> </div> <div> </div> <div><a href="/en/departments/chem/Education/Documents/Influence%20of%20water%20retaining%20additives%20on%20the%20drying%20process%20of%20water%20borne%20paint.pdf">Influence of water retaining additives on the drying process of water borne paint.pdf</a></div></div>Thu, 03 Sep 2015 00:00:00 +0200 self-assembling structures of colloids and cells<p><b>A PhD project performed within SuMo Biomaterials by Oskar Lindgren. Oskar will defend his thesis “Designing self-assembling structures of colloids and cells” on the 27th of May</b></p><strong><img width="133" height="173" src="/en/centres/sumo/news/Documents/Oskar-Lindgren-170x220.jpg" class="chalmersPosition-FloatRight" alt="" style="margin:5px" /><br />What has the main focus of your research project been?</strong><br />- The focus has been to develop theoretical methods for understanding and controlling self-assembly. If you want a certain structure, how do we calculate how they should be designed in different situations, so that they assemble themselves into that desirable structure? <br /><br /><strong>Design of the interaction potential is the key to designing self-assembly </strong><br /><strong>Can you describe Interaction potential</strong><br />- Interaction potential means that; there is an energy that describes how close two particles wants to be to each other, they are at the distance that they want to. In physics, systems tend to seek low energy states. If we design the interaction potential so that a certain distance is preferred, the particles will find a configuration where this distance is prominent. This is the key to designing self-assembly, to figure out which configuration the system will seek from the preferred distances.<br />This interaction potential is a radial function. If you can design this arbitrarily, what can you then do? <br /><br />- Most of the previous studies have been trial and error. By experiments and simulations one has been trying to find a solution that self-assembles into what you desire. We don’t have to try, we calculate.<br /><br /><strong>Don’t you need to do experiments to verify?</strong><br />- Yes, off course, that is an important part. Just that, instead of making experiment after experiment and in that way find the solution we do the opposite, we try to design the solution first an then verify. <br /><br /><strong>Have you been working with a specific system?</strong><br />- No, we have been working with a broad model that will try to capture many different systems. <br /><br />- When designing the system we defines it, what it should look like to function. We don’t know if there is a real system looking like the design. <br /><br /><strong>Can you recreate in real life?</strong><br />- My last article was on alkanethiol coated gold nanoparticles, showing that by designing how these molecules on the surface interact with each other, we can cause many different patterns of spots and stripes to self-assembly on the surface. Those patterns can in turn cause the nanoparticles to self-assemble into more complicated structures.<br /><br /><strong>The design principle in summary</strong><br />- Choose a pattern, calculate the distance between them and how the interactions must occur to make them efficient with low energy. Try, and since they will work, you will receive the pattern you want. If you were clever you will get it also in 3-d structures, as in the picture below. <br /><br />The design principle says, “this is the way to design interactions to make them cause self-assembly of desired systems.<br /><br /><img width="228" height="293" src="/en/centres/sumo/news/Documents/fig5defragged.jpg" class="chalmersPosition-FloatLeft" alt="" style="margin:5px" /><br /><br /><span style="font-size:10px"><em><br /><br /><br /><br /><br /><br /><br /><br /><br />Hierarchical self-assembly of patchy colloids in Monte Carlo simulations. Surface particles with simple isotropic interactions self-assembles into functional patterns that in turn causes the coated colloids to self-assemble into cubic aggregates (b). The interactions that cause the self-assembly was derived using an energy spectrum, the Fourier transform of the interactions (a).</em></span><br /><br /><br /><em><strong><br /><br /><br /><br />SuMo Biomaterials in Short </strong></em><br /><em>SuMo Biomaterials is a Vinnova (Swedish government agency) supported research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.</em><br /><em> </em><br /><em>The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goal to generate added value for industry, academia and society.</em><br /><br />Tue, 19 May 2015 00:00:00 +0200 chairman of the Board for SuMo Biomaterials<p><b>Michael Persson, Innovation Manager at AkzoNobel’s Pulp and Performance Chemicals business, has been appointed as chairman of the Board of SuMo Biomaterials.</b></p><img width="176" height="262" src="/en/centres/sumo/news/Documents/Michael%20Persson_SuMo.jpg" alt="Professor Michael Persson" class="chalmersPosition-FloatLeft" style="height:247px;width:167px;margin:5px" /><br />Michael Persson is, since March 2015, appointed as chairman of the Board of SuMo Biomaterials. Michael Persson is presently Innovation Manager at AkzoNobel’s Pulp and Performance Chemicals business.  He is also Adjunct Professor, Chemistry and Chemical Engineering, Applied Surface Chemistry, since 3 years.<br /> <br /><strong>What are your reflections on SuMo Biomaterials at Chalmers?</strong><br />SuMo Biomaterials has since the start had high ambitions regarding interdisciplinary co-operations in the four modules (diffusion and flow, material and structure, mathematics and computer modelling, materials design) with various university departments and institute as well as with industry. The interdisciplinary way of working has during the years been combined with concrete efforts of implementing the results in the industry. The SuMo way of interacting with companies, if continued at the same high ambition level, may set a new standard how to run big programs with a lot of partners delivering fundamental research as well as direct value to the partners.  <br /> <br /><strong>What would you say is the main task/goal of SuMo Biomaterials?</strong><br />Deliver research of high scientific standard that fulfil the expressed needs from the industry. <br /><br /><strong>What opportunities do you see for SuMo Biomaterials in the coming years at Chalmers ?</strong><br />To maintain the high ambition of delivering results of scientifically and industrial value and planning for how the SuMo concept of working could continue also after the final stage is ended in 2017.<br /><br /><strong>Which are your own research interests?   </strong><br />My research area has been materials science. I started with development of advanced ceramics, continued with development of chemicals for the paper industry as well as development of silica nanoparticles for various applications. The last years I have also been involved in looking into the safety aspects of nanomaterials. <br /> <br /><strong>Tell us a bit about your background.</strong><br />I’m a chemical engineer from Chalmers. I did my research at the Swedish Ceramic Institute (now part of Swerea) but had also a lot of co-operations with the Swedish engineering industry. After the dissertation in the area of ceramics I moved to AkzoNobel Pulp and Performance Chemicals (former Eka Chemicals) where I have had several R&amp;D managers’ positions and since 2012 acting as Innovation Manager.  <br /><strong> </strong><br /><br /><br /><em><strong>SuMo Biomaterials in Short </strong></em><br /><em>SuMo Biomaterials is a Vinnova (Swedish government agency) supported research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.</em><br /><em> </em><br /><em>The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goal to generate added value for industry, academia and society.</em><br />Tue, 31 Mar 2015 00:00:00 +0200 the link between water, microstructure, and texture properties in pasta.<p><b>A PhD project in SuMo Biomaterials by Thomas Steglich, dissertation 6 March.</b></p><p><strong>​We all strive to get that perfect ”al dente” cooked pasta. But what determines the quality of the pasta and why does bran rich pasta have a different texture compared to plain pasta when cooked? The project is about pasta, </strong><strong>what happens when you boil it and what importance does different types of wheat have for the final product. For example why whole-wheat pasta is softer and grittier.</strong>  <br /><img class="chalmersPosition-FloatRight" src="/SiteCollectionImages/Centrum/SuMo/Thomas%20S.jpg" alt="" style="height:138px;width:116px;margin:5px" /></p> <p><strong>Tell about the PhD project</strong><br />- By combining Magnetic Resonance Imaging (MRI) with Light Microscopy we have studied how water migrates within pasta and how it interacts with raw materials used. It does not matter what materials we use if we don’t understand what happens later on. <br />We studied spaghetti with varied gluten, starch and fibre content, as well as fibre particle size. </p> <div> </div> <div><strong>So you used both MRI and Microscopy?</strong><br />-With MRI we could determine the amount of water molecules at any isolated point and visualise the water distribution within pasta in highly resolved 3D images. Combining it with Light Microscopy, we could also illustrate the interactions of water with the different components (gluten, starch and fibre).</div> <div> </div> <div>- We could see that the water was distributed different in various pastas, that the fibre particles in whole-wheat does not let the water thru. Big fibre particles form a barrier against the water migration and the water had to migrate around the particle, which resulted in an uneven starch swelling. However: the smaller the particles, the smaller the effect. </div> <div> <strong><br />What is the result of the study?</strong><br />- With this project we have increased the understanding for what different raw materials do to the pasta structure and how it manifests itself when eating. This knowledge will be used when developing and adjusting pasta products. </div> <div> </div> <div>- Also, by applying this knowledge to bran-rich pasta, we could show that fibres actually can be added without compromising the pasta texture.</div> <div> </div> <div><strong>What will happen next for you?</strong><br />Eventually I hope to end up in the industry, within Food Science or Technology. It was one of the drivers for me taking on this project, that it was an industry project working with real products.</div> <div> </div> <div><em>This PhD project was funded by the Lantmännen and is a project within SuMo Biomaterials</em></div> <div><br /><strong>What is SuMo Biomaterials?</strong><br /><a href="/en/centres/sumo/Pages/default.aspx">SuMo Biomaterials</a> VINN Excellence centre is a Vinnova (Swedish government agency) supported research consortium between academia (Chalmers University of Technology and SP Food and Bioscience) and industry (AkzoNobel, AstraZeneca, Lantmännen, Mölnlycke Health Care, SCA, Stora Enso and Tetra Pak). The focus of the centre is on understanding and developing properties of soft biomaterials.</div> <div> </div> <div>The concept of SuMo Biomaterials is to use industrial needs to create innovations and academic excellence in science with the long term goals to generate added values for industry, academia and society.<br /></div>Wed, 04 Mar 2015 00:00:00 +0100