Gulshan Rameshrao Walke


Dr. Gulshan Walke joined the Wittung-Stafshede research group as a postdoc in 2021. The main focus is to elucidate the mechanisms of copper-binding proteins in cancer and the role of copper in the function and dysfunction of amyloidogenic proteins, such as alpha-synuclein. This also involves looking for the putative roles of redox chemistry associated with these proteins' functions. His work might bring new directions in the role of copper in cancer pathology.
1. Walke GR, Ruthstein S. Does the ATSM-Cu(II) biomarker integrate into the human cellular copper cycle? ACS Omega. 2019;4, 12278-12285.

2. *Santoro A, *Walke GR, Vileno B, Kulkarni PP, Raibaut L, Faller P. Low catalytic activity of the Cu(II)-binding motif (Xxx-Zzz-His; ATCUN) in reactive oxygen species production and inhibition by the Cu(I)-chelator BCS. Chem Commun (Camb) 2018;54(84):11945-11948.

3. Walke GR, Ranade DS, Ramteke SN, Rapole S, Satriano C, Rizzarelli E, Tomaselli GA, Trusso Sfrazzetto G, Kulkarni PP. Fluorescent Copper Probe Inhibiting Abeta1-16-Copper(II)-Catalyzed Intracellular Reactive Oxygen Species Production. Inorg Chem 2017;56(7):3729-3732.

Page manager Published: Fri 11 Feb 2022.