Fredrik Westerlund

Professor; Biology and Biological Engineering
Head of Division of Chemical Biology

fredrik.westerlund@chalmers.se +46317723049 Find me http://orcid.org/0000-0002-4767-4868

Fredrik Westerlund's research is devoted to studying single DNA molecules in nanofluidic channels using fluorescence microscopy. Focus is directed both towards developing new techniques to map DNA sequences as well as for studying DNA-protein interactions.

Westerlunds Research Group

Publications - ResearcherID

Teaching
Publications
Collaboration and projects

Biophysical chemistry (KFK021), Lecturer

Latest publications

2022
Nanofluidic Trapping of Faceted Colloidal Nanocrystals for Parallel Single-Particle Catalysis

Author: Sune Levin; Sarah Lerch; Astrid Boje; Joachim Fritzsche; Sriram Kesarimangalam; Henrik Ström; Kasper Moth-Poulsen; Henrik Sundén; Anders Hellman; Fredrik Westerlund; Christoph Langhammer

Published: 2022

Published in: ACS Nano

Publication type: Journal article
Nanofluidic Trapping of Faceted Colloidal Nanocrystals for Parallel Single-Particle Catalysis

Author: Sune Levin; Sarah Lerch; Astrid Boje; Joachim Fritzsche; Sriram Kesarimangalam; Henrik Ström; Kasper Moth-Poulsen; Henrik Sundén; Anders Hellman; Fredrik Westerlund; Christoph Langhammer

Published: 2022

Published in: ACS Nano

Publication type: Journal article
HnRNPK maintains single strand RNA through controlling double-strand RNA in mammalian cells

Author: Sagar Mahale; Meenakshi Setia; Bharat Prajapati; Santhilal Subhash; Mukesh Pratap Yadav; Subazini Thankaswamy; Ananya Deshpande; Jagannath Kuchlyan; Mirco Di Marco; Fredrik Westerlund; Marcus Wilhelmsson; Chandrasekhar Kanduri; Meena Kanduri

Published: 2022

Published in: Nature Communications

Publication type: Journal article
Label-free nanofluidic scattering microscopy of size and mass of single diffusing molecules and nanoparticles

Author: Barbora Spackova; Henrik Klein Moberg; Joachim Fritzsche; Johan Tenghamn; Gustaf Sjosten; Hana Jungová; David Albinsson; Quentin Lubart; Daniel van Leeuwen; Fredrik Westerlund; Daniel Midtvedt; Elin Esbjörner Winters; Mikael Käll; Giovanni Volpe; Christoph Langhammer

Published: 2022

Published in: Nature Methods

Publication type: Journal article
A simple cut and stretch assay to detect antimicrobial resistance genes on bacterial plasmids by single-molecule fluorescence microscopy

Author: Gaurav Goyal; Elina Ekedahl; My Nyblom; Jens Krog; Erik Frobrant; Magnus Brander; Tsegaye Sewunet; Teerawit Tangkoskul; Christian G. Giske; Linus Sandegren; Visanu Thamlikitkul; Tobias Ambjornsson; Fredrik Westerlund

Published: 2022

Published in: Scientific Reports

Publication type: Journal article
Organic Anisotropic Excitonic Optical Nanoantennas

Author: Evan S.H. Kang; Sriram Kesarimangalam; Inho Jeon; Jehan Kim; Shangzhi Chen; Kyoung-Ho Kim; Ka-Hyun Kim; Hyun Seok Lee; Fredrik Westerlund; Magnus P. Jonsson

Published: 2022

Published in: Advanced Science

Publication type: Journal article
Left versus right: Exploring the effects of chiral threading intercalators using optical tweezers

Author: Adam A. Jabak; Nicholas Bryden; Fredrik Westerlund; Per Lincoln; M. J. McCauley; I. Rouzina; Mark C. Williams; T. Paramanathan

Published: 2022

Published in: Biophysical Journal

Publication type: Journal article
Nanofluidics for single DNA molecule analysis of DNA repair

Author: Fredrik Westerlund

Published: 2022

Published in: Biophysical Journal

Publication type: Other text in scientific journal
Polyclonal spread of blaCTX-M-15 through high-risk clones of Escherichia coli at a tertiary hospital in Ethiopia

Author: Tsegaye Sewunet; Daniel Asrat; Yimtubezinash Woldeamanuel; Sofia Ny; Fredrik Westerlund; Abraham Aseffa; Christian G. Giske

Published: 2022

Published in: Journal of Global Antimicrobial Resistance

Publication type: Journal article
Quantification of single-strand DNA lesions caused by the topoisomerase II poison etoposide using single DNA molecule imaging

Author: Vandana Singh; Pegah Johansson; Elina Ekedahl; Yii Lih Lin; Ola Hammarsten; Fredrik Westerlund

Published: 2022

Published in: Biochemical and Biophysical Research Communications

Publication type: Journal article
High diversity of blaNDM-1-encoding plasmids in Klebsiella pneumoniae isolated from neonates in a Vietnamese hospital

Author: Sriram Kesarimangalam; Elina Ekedahl; Ngoc Thi Bich Hoang; Tsegaye Sewunet; Björn Berglund; Ludwig Lundberg; Shoeib Nematzadeh; Maud Nilsson; Lennart E. Nilsson; Ngai Kien Le; Tran Minh Dien; Håkan Hanberger; Linus Olson; Mattias Larsson; Christian G. Giske; Fredrik Westerlund

Published: 2022

Published in: International Journal of Antimicrobial Agents

Publication type: Journal article
2021
CRISPR/CAS9 BASED DNA-COMBING ASSAY FOR DETECTING ANTIMICROBIAL RESISTANCE GENES ON PLASMIDS

Author: Gaurav Goyal; Elina Ekedahl; My Nyblom; Jens Krog; Erik Torstensson; Tsegaye Sewunet; Christian G. Giske; Visanu Thamlikitkul; Tobias Ambjörnsson; Fredrik Westerlund

Published: 2021

Published in: MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Publication type: Paper in proceeding
Combining dense and sparse labeling in optical DNA mapping

Author: Erik Torstensson; Gaurav Goyal; Anna Johnning; Fredrik Westerlund; Tobias Ambjörnsson

Published: 2021

Published in: PLoS ONE

Publication type: Journal article
Click and Cut: a click chemistry approach to developing oxidative DNA damaging agents

Author: Natasha McStay; Creina Slator; Vandana Singh; Alex Gibney; Fredrik Westerlund; Andrew Kellett

Published: 2021

Published in: Nucleic Acids Research

Publication type: Journal article
Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach

Author: Albertas Dvirnas; Callum L. Stewart; Vilhelm Müller; Santosh Kumar Bikarolla; Karolin Frykholm; L. Sandegren; Erik Kristiansson; Fredrik Westerlund; Tobias Ambjörnsson

Published: 2021

Published in: PLoS ONE

Publication type: Journal article
A parallelized nanofluidic device for high-throughput optical dna mapping of bacterial plasmids

Author: Sriram Kesarimangalam; Yii Lih Lin; Tsegaye Sewunet; Marie Wrande; L. Sandegren; Christian G. Giske; Fredrik Westerlund

Published: 2021

Published in: Micromachines

Publication type: Journal article
High prevalence of bla(CTX-M-15) and nosocomial transmission of hypervirulent epidemic clones of Klebsiella pneumoniae at a tertiary hospital in Ethiopia

Author: Tsegaye Sewunet; Daniel Asrat; Yimtubezinash Woldeamanuel; Sofia Ny; Fredrik Westerlund; Abraham Aseffa; Christian G. Giske

Published: 2021

Published in: JAC-ANTIMICROBIAL RESISTANCE

Publication type: Journal article
Optical dna mapping of plasmids reveals clonal spread of carbapenem-resistant klebsiella pneumoniae in a large thai hospital

Author: Sriram Kesarimangalam; Tsegaye Sewunet; Walaiporn Wangchinda; Teerawit Tangkoskul; Visanu Thamlikitkul; Christian G. Giske; Fredrik Westerlund

Published: 2021

Published in: Antibiotics

Publication type: Journal article
Complex conformational dynamics of the heart failure‐associated pre‐mirna‐377 hairpin revealed by single‐molecule optical tweezers

Author: Anna Wiktoria Wypijewska Del Nogal; Vinoth Sundar Rajan; Fredrik Westerlund; Marcus Wilhelmsson

Published: 2021

Published in: International Journal of Molecular Sciences

Publication type: Journal article
Identity of blactx-m carrying plasmids in sequential esbl-e. Coli isolates from patients with recurrent urinary tract infections

Author: N. Karami; Sriram Kesarimangalam; Shora Yazdanshenas; Yii Lih Lin; Daniel Jaén-Luchoro; Elina Ekedahl; Sanjana Parameshwaran; Anna Lindblom; Christina Åhrén; Fredrik Westerlund

Published: 2021

Published in: Microorganisms

Publication type: Journal article
Shining light on single-strand lesions caused by the chemotherapy drug bleomycin

Author: Vandana Singh; Pegah Johansson; Yii Lih Lin; Ola Hammarsten; Fredrik Westerlund

Published: 2021

Published in: DNA Repair

Publication type: Journal article
The HIV-1 nucleocapsid chaperone protein forms locally compacted globules on long double-stranded DNA

Author: Kai Jiang; Nicolas Humbert; Sriram Kesarimangalam; I. Rouzina; Yves Mely; Fredrik Westerlund

Published: 2021

Published in: Nucleic Acids Research

Publication type: Journal article
Single Molecule Experiments Define the Role of Nbs1 and Xrs2 in DNA Tethering by MRN and MRX in DSB Repair

Author: Carl Ivar Möller; Rajhans Sharma; Robin Öz; Giordano Reginato; Elda Cannavo; Sriram Kesarimangalam; Petr Cejka; Fredrik Westerlund

Published: 2021

Published in:

Publication type: Other conference contribution
Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis

Author: Robin Öz; Jing L. Wang; Raphael Guerois; Gaurav Goyal; Sriram Kesarimangalam; Virginie Ropars; Rajhans Sharma; Firat Koca; Jean Baptiste Charbonnier; M. Modesti; Terence R. Strick; Fredrik Westerlund

Published: 2021

Published in: Nucleic Acids Research

Publication type: Journal article
Polyphasic characterization of carbapenemresistant Klebsiella pneumoniae clinical isolates suggests vertical transmission of the blaKPC-3gene

Author: Catarina Ferreira; Santosh Kumar Bikarolla; Karolin Frykholm; Saga Pohjanen; Margarida Brito; Catarina Lameiras; O. C. Nunes; Fredrik Westerlund; C. M. Manaia

Published: 2021

Published in: PLoS ONE

Publication type: Journal article

Go to Chalmers publication library

Projects
1/1/2020 — 12/31/2022

Förbättrad cancerbehandling av barn känsliga för DNA-skador
1/1/2020 — 12/31/2022

Förbättrad diagnos av akut leukemi hos barn
1/1/2020 — 12/31/2022

Identification of bacterial infections and antibiotic resistance in low income countries by rapid...
1/1/2021 — 12/31/2023

Identifying molecular mechanisms causing sensitivity to chemotherapy
4/1/2020 — 3/31/2025

Next Generation Nanofluidic Devices for Single Molecule Analysis of DNA Repair Dynamics
1/1/2021 — 12/31/2024

Real-Time Visualization of DNA Repair - One Molecule at a Time
Closed
1/1/2012 — 12/31/2015

A nanofluidic platform for single molecule biophysics
8/1/2017 — 7/31/2019

A novel ultrafast method for detecting multiresistant bacteria in intensive care units
12/1/2019 — 9/30/2020

Basal oxidative damage level assay (BODLA)
1/1/2017 — 12/31/2019

Bärbar diagnostik för sjukdom och antibiotikaresistans med fokus på malaria och bakterieinfektioner
11/1/2016 — 4/30/2018

Characterization of bacterial plasmids on a smartphone
8/24/2020 — 5/17/2021

Detection and characterization of chromosomal translocations in acute leukemia using optical DNA...
6/1/2015 — 12/31/2019

Genomic diagnostics beyond the sequence (BeyondSeq)
1/1/2018 — 12/31/2020

Individanpassning av cancerbehandling med cellgifter genom direkt mätning av DNA-skador
1/1/2017 — 12/31/2019

Mätning av DNA-skador som ett sätt att individanpassa cancerbehandling med cellgifter
1/1/2014 — 12/31/2016

Nanofluidics for ultrafast diagnosis of bacterial infections (NanoDiaBac)
1/1/2015 — 12/31/2016

Odlingsfri identifiering av antibiotikaresistens
4/1/2018 — 12/31/2020

Plasmididentifikation och -detektion i Sydostasien - Enterobacteriaceae resistenta mot sista...
7/1/2016 — 12/31/2018

Studier av DNA-reparation på enskilda DNA-molekyler

Page manager Published: Tue 01 Sep 2020.

Fredrik Westerlund

Latest publications

2022

2021

Projects

Closed