Erdem Karabulut

PhD; Chemistry and Chemical Engineering, Applied Chemistry, Biopolymer Technology

3D printing is a revolutionary technology for engineering materials with advanced functionality and versatile design. It is possible to have a rapid manufacturing of 3D tissue models and organs in the laboratory conditions. The biocompatible inks, mimicking the chemical and physical properties of extracellular matrix (ECM), are a great of need for 3D bioprinting of soft tissues.
My research relies on the design of cell-laden biopolymer- and hydrogel-based bio-inks for the preparation of tissue models using 3D printers. This design covers a wide range of bio-ink tests including gelation, colloidal and rheological properties, printability, cross-linking and solidification after printing, long-term stability in media, cell viability, and stimulation of cells during tissue growth. I pursue studies on the chemical and physical modification of biopolymers and nanoparticles with ECM components to improve the cell adhesion and migration in the 3D constructs. I have been pursuing on 3D printed skin and neuronal tissue models using dermal fibroblasts, keratinocytes and human neuroblastoma cells.

Published: Tue 08 Dec 2015. Modified: Tue 27 Nov 2018