Page manager Published: Fri 08 Mar 2013.

World premiere of muscle and nerve controlled arm prosthesis

PRESS RELEASE: For the first time an operation has been conducted, at Sahlgrenska University Hospital, where electrodes have been permanently implanted in nerves and muscles of an amputee to directly control an arm prosthesis. The result allows natural control of an advanced robotic prosthesis, similarly to the motions of a natural limb.

A surgical team led by Dr Rickard Brånemark, Sahlgrenska University Hospital, has carried out the first operation of its kind, where neuromuscular electrodes have been permanently implanted in an amputee. The operation was possible thanks to new advanced technology developed by Max Ortiz Catalan, supervised by Rickard Brånemark at Sahlgrenska University Hospital and Bo Håkansson at Chalmers University of Technology.

“The new technology is a major breakthrough that has many advantages over current technology, which provides very limited functionality to patients with missing limbs,” says Rickard Brånemark.

Big challenges
There have been two major issues on the advancement of robotic prostheses: 1) how to firmly attach an artificial limb to the human body; 2) how to intuitively and efficiently control the prosthesis in order to be truly useful and regain lost functionality.

“This technology solves both these problems by combining a bone anchored prosthesis with implanted electrodes,” said Rickard Brånemark, who along with his team has developed a pioneering implant system called Opra, Osseointegrated Prostheses for the Rehabilitation of Amputees.

A titanium screw, so-called osseointegrated implant, is used to anchor the prosthesis directly to the stump, which provides many advantages over a traditionally used socket prosthesis.

“It allows complete degree of motion for the patient, fewer skin related problems and a more natural feeling that the prosthesis is part of the body. Overall, it brings better quality of life to people who are amputees,” says Rickard Brånemark.

How it works
Presently, robotic prostheses rely on electrodes over the skin to pick up the muscles electrical activity to drive few actions by the prosthesis. The problem with this approach is that normally only two functions are regained out of the tens of different movements an able-body is capable of. By using implanted electrodes, more signals can be retrieved, and therefore control of more movements is possible. Furthermore, it is also possible to provide the patient with natural perception, or “feeling”, through neural stimulation.

“We believe that implanted electrodes, together with a long-term stable human-machine interface provided by the osseointegrated implant, is a breakthrough that will pave the way for a new era in limb replacement,” says Rickard Brånemark.

The patient
The first patient has recently been treated with this technology, and the first tests gave excellent results. The patient, a previous user of a robotic hand, reported major difficulties in operating that device in cold and hot environments and interference from shoulder muscles. These issues have now disappeared, thanks to the new system, and the patient has now reported that almost no effort is required to generate control signals. Moreover, tests have shown that more movements may be performed in a coordinated way, and that several movements can be performed simultaneously.

“The next step will be to test electrical stimulation of nerves to see if the patient can sense environmental stimuli, that is, get an artificial sensation. The ultimate goal is to make a more natural way to replace a lost limb, to improve the quality of life for people with amputations,” says Rickard Brånemark.

Caption, top picture: The neuromuscular electrodes are permanently implanted, while the osseointegrated prosthesis can be dismounted. Watch an animation here

More on the research project

This is a multidisciplinary project conducted as a cooperation between the Sahlgrenska University Hospital, Sahlgrenska Academy, Chalmers University of Technology and Integrum AB. Collaboration between several different disciplines – medicine, biomaterials, mechatronics, analog and digital electronics, artificial Intelligence, biomechanics and so forths – is a prerequisite for this complex work. The project is financed by Vinnova, ALF (A general agreement between Swedish County Councils and the Swedish Government on cooperation in medical training and research) and Promobilia Foundation.

Rickard Brånemark, Director at the Centre of Orthopaedic Osseointegration, Sahlgrenska University Hospital and Associate Professor at the Sahlgrenska Academy, University of Gothenburg, +46-70-846 1061,

Max Ortiz Catalan, PhD Student, Chalmers, +46 70-846 1065,
Bo Håkansson, Professor, Chalmers +46 70-785 3294,​

See also an earlier press release from this project:
Thought-controlled prosthesis is changing the lives of amputees

Page manager Published: Fri 08 Mar 2013.