Image processing, Spatial statistics

Spatial analysis and modelling of epidermal nerve fibre patterns

Preliminary neurologic studies indicate qualitative differences in the spatial patterns of epidermal nerve fibers (ENF) based on pathophysiological conditions in the subjects. Our goal is to quantify differences in the spatial pattern of ENFs in normal subjects (without neuropathy) from the patterns in subjects with neuropathy. Of particular interest is the progress of diabetic neuropathy and it is studied by analysing the data from the Kennedy Laboratory, Department of Neurology, School of Medicine, University of Minnesota. First, we apply second order methods of spatial point and fibre processes to the ENF data, and second, some models for the ENF patterns are suggested.


Collaboration partners:

Lance A. Waller
Department of Biostatistics
Rollins School of Public Health
Emory University

William R. Kennedy
and Gwen Wendelschafer-Crabb
Department of Neurology School of Medicine
University of Minnesota

Published: Tue 05 Feb 2013. Modified: Tue 12 Sep 2017