Events: Data- och informationsteknik events at Chalmers University of TechnologyThu, 10 Aug 2017 14:52:30 +0200 Wånggren, Computer Science and Engineering<p>ES51, lecture room, Linsen, EDIT</p><p>Protein modelling by the zipping and assembly method with limited NMR-derived constraints</p>Molecular dynamics simulations, often combined with simulated annealing, are commonly used when calculating structural models of proteins, e.g. based on NMR experiments. However, one is often faced with limited and, sometimes, insufficient information for determining a well-resolved 3D structure. In addition, the type of data available for different proteins may vary: ranges for torsion angles, distance ap- proximations, relative orientation of different molecular parts etc. We are using whatever structural information is around, together with a dynamic programming approach (Zipping and Assembly) for searching the space of feasible conformations to rapidly determine 3D structures that are consistent with the input constraints. Time-efficiency is im- portant for good sampling of the conformational space and necessary to replace expensive, complex and time consuming experiments. Our approach benefits from having both high level and low level descriptions of conformational features and constraints and the possibility to infer new constraints from those that are given. ACM Symposium on Virtual Reality Software and Technology (VRST) 2017<p>Chalmers Lindholmen, Gothenburg</p><p>​VRST will provide an opportunity for VR researchers to interact, share new results, show live demonstrations of their work, and discuss emerging directions for the field.</p>​ <br />The ACM Symposium on Virtual Reality Software and Technology (VRST) is an international forum for the exchange of experience and knowledge among researchers and developers concerned with virtual reality software and technology. <br /><br /><a href="">To conference website:</a><br /><br />