Ann-Sofie Sandberg, Professor
Alastair Ross, Associate Professor
Malin Barman, PhD
Karin Larsson PhD
Mia Andersson MSc student
Olle Hartvigsson MSc student
Allergic disease is a major problem in Western society in particular, and the most common chronic disease among children in Sweden. There is currently no evidence-based strategy to reduce the risk of allergy. The role of maternal environment and microbiota is emerging as an important factor determining the prevention and development of childhood allergy and other immune related diseases.
Our research investigates the effects of maternal diet and early life nutrition on immune maturation with focus on allergy prevention in infants. We work in two mother child birth cohorts: NICE and FARMFLORA
NICE: The overall aim is to study how the environment – nutrition, microbes, and environmental toxins - during pregnancy and the first years of life influence maturation of the immune system and development of immune mediated and neurological diseases. (extensive biobank, multi omics methodologies) The goal is to find novel strategies for prevention and prediction of allergy.
FARMFLORA: To identify factors (diet and nutrients, gut and airway microbiota) that may be part of the allergy protection of the farming environment.
Collaborations: Sahlgrenska Academy, Sunderby Hospital Karolinska Institute, Umeå University