Metabolism – The Foundation of Life
is essential for us as it deals with the uptake and transformation of
nutrients to sustain life. There are three important aspects of
metabolism – the chemical breakdown of energy-rich molecules to supply
energy, the synthesis of building blocks to build cells and organisms,
and the elimination of waste products. These processes are essential for
life – where there is metabolism there is life and without metabolism
there is no life.
this in mind, it is not surprising that metabolic dysfunction is a
common cause of disease. It plays an important role in “metabolic
diseases” such as mitochondrial diseases, type 2 diabetes, and
cardiovascular diseases. There is also increasing evidence that
metabolic dysregulation contributes to diseases that perhaps are not
directly thought of as “metabolic diseases” such as neurodegenerative
conditions and diseases affecting the liver, lungs and kidneys.
are not alone; we coexist with our microbiome and this relationship is
important for metabolic regulation. Another interesting aspect of the
metabolism is that metabolic pathways can be engineered to learn new
tricks and help us produce valuable compounds such as fuels, chemicals
program is an attempt to cover some of the many interesting subjects
within the field of metabolism. These topics have been selected to give
glimpses of interesting areas that we think will be important in
providing new information, new procedures, and new treatments for the
good of everyone.