Porous biodegradable polymeric implants
The goal is to coat metallic screws for implants with biodegradable polymeric coatings with the aim to deliver drugs for improved bone growth for patients. Biodegradable polymer film coatings were made by a water-in-oil emulsion method where the biodegradable polymers were dissolved in the organic phase and the lithium in the water phase. By using different ionic strength in the water phase the pore structure could be controlled. Different coating methods like dipping, spray coating and electro spin coating have been evaluated. The mass transport rate of radioactive labelled water through casted films could be related to the pore structure and lithium release. The project is in collaboration with the group of Prof. Pentti Tengvall, Gothenburg University, where animal tests will be performed during the autumn, and SuMo projects including the barrier project, the interface and macroscopic swelling project.
Last modified: September 20, 2011